Optimal Control Using Causal Agents

Translational Synergies in Causal Inference and Reinforcement Learning

MaryLena Bleile, Ph.D.

See the matrix. Bridge fields without apology.

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About This Book

Optimal Control Using Causal Agents is a translation manual between Causal Inference and Reinforcement Learning, written for researchers and practitioners already familiar with either Causal Inference or Reinforcement Learning. Each theoretical connection is grounded in concrete applications ranging from clinical decision-making and Brazilian Jiu-Jitsu strategy to GARCH financial modeling. The book uses R and Python for implementation.

Optimal Control Using Causal Agents is a rosetta stone, not a comprehensive textbook (see the Causal AI book developed by Bareinboim, et. al. for that). In short, Optimal Control Using Causal Agents builds bridges between existing concepts instead of constructing concepts from the ground up. The goal is for causal inference practitioners to gain instant access to reinforcement learning's computational tools by seeing how these tools share ideas with their causal methods, and vice versa. The result is a practical guide for navigating 70 years of parallel mathematical development that has been artificially separated by academic boundaries. Perhaps the most important contribution is a comprehensive translation table which creates a map between notational conventions in both fields.

Publisher: CRC Press

Expected Publication: Spring 2026

Series: Chapman & Hall/CRC Press

Editor: Lara Spieker

Table of Contents

Part I: The Divide

  1. Introduction [pdf]
  2. Programming [Code] [pdf]

Part II: Foundations: Causal Inference

  1. Causal Inference With Randomization [Code][pdf]
  2. Causal Inference Without Randomization [Code][pdf]

Part III: Foundation and Empire: Bridges From Reinforcement Learning to Causal Inference

  1. Tabular Reinforcement Learning [Code][pdf]
  2. Reinforcement Learning Models [Code]

Part IV: Second Foundation: Synthesis

  1. Beyond Markovian Dynamics
  2. Beyond Ignorable Missing Data

Resources

Tour Dates

May
2026
7th Ace Drug Discovery Summit
San Diego, CA
Invited Talk
2026
BioTechX 2026
Boston, MA
Invited Talk
2026
NxtAI 2026
Boston, MA
Invited Talk
2026
University of Utah
Salt Lake City, UT
Invited Guest Seminar
Aug
2026
JSM 2026: Causality and Complex Dynamic Systems
Bridging Statistical Inference and Control Theory
Special Topic Panel